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KMID : 0363219920300060871
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Korean Journal of Dermatology
1992 Volume.30 No. 6 p.871 ~ p.879
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Optimal Method of Intralesional Corticosteroid Injection in the Treatment of Alopecia areata
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Abstract
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Intralesional injection of adrenal corticosteroids has widely been used in the treatment of alopecia areata. But the concentration of the drug and the interval of the injection are greatly different among the physicians practicing the method. The
author
evaluated the therapeutic results and untoward effects of the intralesional injections using two different concentrations on the same lesion devided into two or on the two simultaneousely occurred lesions in each patient to make exact comparsion
of
the
different concentrations in total 24 patients.
Intralesional injections with triamcinolone acetonide 5mg/ml at 2 week interval showed appreciable hair regrowing in 4 weeks in 62.5% while 1mg/ml of the drug at equal interval showed appreciable hair regrowing in 6 weeks in 66.7%. But in the
group
of
5mg/ml, 16.7% ot fhe lesions showed considerable delay of the hair growing because of the atropy of the skin and hair follicle while no such delay was found in the group of 1mg/ml.
With the above data, the best results would be expected by the concentration between 1mg/ml and 5mg/ml in case of triamcinolone acetonide intralesional injection at 2 week intervals. (Kor J Dermatol 1992;30(6) :871-879)
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KEYWORD
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